Okur-Chung Neurodevelopmental Syndrome (OCNDS) is caused by heterozygous mutations to the CSNK2A1 gene, which encodes the alpha subunit of protein kinase CK2.The most frequently occurring mutation is lysine 198 to arginine (K198R).To investigate the impact of this mutation, we first generated a high-resolution phosphorylation motif of CK2WT, includ

The claustrum is a narrow subcortical brain structure that resides between the striatum and insular cortex.The function of the claustrum is not fully described, and while our previous work supports a role for the claustrum in top-down cognitive control ALL PURPOSE CL of action, other evidence suggests the claustrum may be involved in detecting sali